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A variety of media, supplemental media components, and reagents suitable for cell culture operations and processes. Products include fully prepared media as well as antibiotics, growth factors, contamination detection and removal reagents, cell dissociation reagents, and more.
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RF9 hydrochloride is a potent and selective Neuropeptide FF receptor antagonist with Ki values of 58 and 75 nM for hNPFF1R and hNPFF2R respectively[1 [2
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Ixazomib (MLN2238) inhibits the chymotrypsin-like proteolytic ( 5) site of the 20S proteasome with IC50 and Ki of 3 4 nM and 0 93 nM in cell-free assays respectively also inhibits the caspase-like ( 1) and trypsin-like ( 2) proteolytic sites with IC50 of 31 and 3500 nM Ixazomib (MLN2238) induces autophagy Phase 3
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Interleukin-12 subunit alpha (IL-12A IL-12p35) an immune-suppressive cytokine encodes a subunit of the cytokine IL-12 that acts on T and natural killer cells and has a broad array of biological activities IL-12A heterodimerizes with IL-12B to form the IL-12 cytokine or with EBI3/IL27B to form the IL-35 cytokine[1][2] IL-12 Protein Human (547a a HEK293 His) is produced in HEK293 cells with a C-Terminal His-tag It consists of IL-12A (M1-S219) and IL-12B (M1-S328)
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VU0155041 is a small-molecule positive allosteric modulator of metabotropic glutamate receptor 4 (mGluR4) used in preclinical neuroscience and pharmacology research. It has reported EC50 values of approximately 798 nM (human) and 693 nM (rat), a molecular weight of 316.18 Da, molecular formula C14H15Cl2NO3, and CAS 1093757-42-6. The compound is supplied at high purity for laboratory research use only.
Potent, selective positive allosteric modulator of mGluR4.
Demonstrated activity in human and rat mGluR4 assays.
High purity for reproducible experimental results.
Soluble in DMSO for assay preparation.
Available in small research pack sizes suitable for preclinical studies.
Supplied for laboratory research use only.
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MMP-8 also known as matrix metalloproteinase-8 or collagenase-2 is recognized for its enzymatic abilities particularly its ability to break down fibrillar types I II and III collagen This enzymatic activity suggests that MMP-8 plays an important role in the remodeling and turnover of collagen-rich tissues such as connective tissue cartilage and bone MMP-8 Protein Human (HEK293 His) is the recombinant human-derived MMP-8 protein expressed by HEK293 with C-10 His labeled tag
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Activin AB protein is a member of the transforming growth factor- (TGF- ) superfamily and plays a key role in various biological processes such as cell differentiation proliferation and apoptosis It is involved in embryonic development tissue repair and immune regulation FGF-9 Protein Human (HEK293 N-hFc) is the recombinant human-derived FGF-9 protein expressed by HEK293 with N-hFc labeled tag
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The CD6 protein is a cell adhesion molecule that mediates cell-cell contacts and regulates T cell responses through interaction with ALCAM/CD166 It functions as a costimulatory molecule promoting T cell activation proliferation and contributing to the formation of immune synapses CD6 Protein Human (HEK293 Fc) is the recombinant human-derived CD6 protein expressed by HEK293 with C-hFc labeled tag
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The CD6 protein is a cell adhesion molecule that mediates cell-cell contacts and regulates T cell responses through interaction with ALCAM/CD166 It functions as a costimulatory molecule promoting T cell activation proliferation and contributing to the formation of immune synapses CD6 Protein Human (HEK293 Fc) is the recombinant human-derived CD6 protein expressed by HEK293 with C-hFc labeled tag
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The CD45 protein is a multifunctional member of the protein tyrosine phosphatase family with heparan sulfate proteoglycan and heparin binding activity as well as protein tyrosine phosphatase activity It plays a crucial role in lymphocyte differentiation macromolecular metabolic processes and signal transduction regulation CD45 Protein Mouse (HEK293 Fc) is the recombinant mouse-derived CD45 protein expressed by HEK293 with C-hFc labeled tag
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CD6 a protein lacks essential conserved residue(s) necessary for propagating feature annotation CD6 Protein Rat (HEK293 His) is the recombinant rat-derived CD6 protein expressed by HEK293 with C-His labeled tag
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The CD5 protein is a potential receptor that regulates T cell proliferation Its interactions with CD72/LYB-2 and PTPN6/SHP-1 indicate multifaceted roles in cellular processes serving as key mediators of T cell responses CD5 Protein Human (HEK293 His) is the recombinant human-derived CD5 protein expressed by HEK293 with C-His labeled tag
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